Jennifer Aniston and Vince Vaughn may have won this year's Teen Choice Award for best chemistry, but a couple of their co-stars in "The Break-Up" clearly know a bit about chemistry, too.

On Tuesday, actors John Michael Higgins and Jon Favreau joined their wives to welcome new children.

It was a boy for Higgins, perhaps best-known for his role in Christopher Guest's "Best in Show," and actress-wife Margaret Welsh. Walter Lloyd Higgins weighed 8 pounds, 2 ounces, Higgins' publicist Jeff Raymond said.

"Parents and baby are doing well," Raymond said. The couple, who live in Los Angeles, also have a 2-year-old daughter, Maisie.

Favreau and physician-wife Joya welcomed their third child, a 6-pound, 13-ounce girl named Brighton Rose Favreau, publicist Bebe Lerner said Thursday.

The couple's other children: Max, 5, and Madeleine, 3.

Higgins, 43, appears in Guest's next film, "For Your Consideration," due in November, and recently completed filming Universal's "Evan Almighty."