Siegelman, 60, was accused of trading government favors for campaign donations when he was governor from 1999 to 2003 and lieutenant governor from 1995 to 1999.
Scrushy was accused of arranging $500,000 in donations to Siegelman's campaign for a state lottery in exchange for a seat on a state hospital regulatory board.
The case was tried as Siegelman sought the Democratic nomination for governor, and the trial put him in court during the final weeks of the campaign. He lost to Lt. Gov. Lucy Baxley in the June 6 Democratic primary and blamed the charges for his defeat.
Prosecutors described a "pay-to-play" scheme in which campaign donations were necessary to participate in government projects.
But defense attorneys said the case was based on the testimony of former Siegelman aide Nick Bailey, lobbyist Lanny Young and toll bridge developer Jim Allen, who they called "scam artists and liars."
Defense attorneys said that Young and Bailey, who have both pleaded guilty, lied on the witness stand in hopes of getting light sentences, and that Allen lied to keep from being charged.
Prosecutors claimed Siegelman and his chief of staff, Paul Hamrick, received gifts, including a Honda motorcycle for the governor that he allegedly tried to conceal from investigators. Hamrick reportedly received $25,000 for a new luxury BMW automobile.
The jury returned the verdict after 11 days of deliberations.
Hamrick and former state transportation director Mack Roberts were acquitted on all charges.