"I strongly condemn the killings that took place, the innocent life lost in Egypt," Bush said. "This is a heinous act against innocent civilians."
He commented at the Venetian Resort Hotel Casino where he was speaking to raise money for Republican Rep. Jon Porter.
The explosions hit the central part of Dahab at nightfall. The resort town is on the Gulf of Aqaba, not far from the Israeli border.
"The United States sends our condolences to the families of those who were killed," Bush said. "We keep those were injured in our thoughts and prayers and I assure the enemy this — we will stay on the offense, we will not waver, we will not tire, we will bring you to justice for the sake of peace and humanity."