Megan Mullally's (search) daytime syndicated talk-variety show has been sold in four top markets for a fall 2006 launch.

The not-yet-titled series has been picked up by NBC owned-and-operated stations in New York, Los Angeles, Chicago and San Francisco, NBC Universal Domestic Television Distribution (search) announced this week.

Mullally has "unique talents as a host, singer and Emmy Award-winning comedic actress," Barry Wallach, president of NBC Universal Domestic Television Distribution, said in a statement.

"The feedback we have received from the advertising and broadcasting communities is one of excitement, as they clearly recognize Megan as a fresh new personality for daytime," he said.

Mullally's daily, one-hour show will air from Los Angeles.

The 46-year-old actress won an Emmy in 2000 for her role as Karen Walker on NBC's "Will & Grace (search)," now in its eighth and final season.