Watch "The Big Story" weekdays at 5 p.m. ET

Karl Rove (search), the White House deputy chief of staff and longtime adviser to President Bush, agrees to testify again on the leak of a CIA officer's name without protection against indictment. We'll get the legal breakdown from Judge Andrew Napolitano, FOX News' senior judicial analyst.

Then, fears of a massive outbreak of the bird flu. The top federal health official says no one in the world is ready right now. The bird flu has killed more than 60 people since emerging in Asia two years ago. So how serious of a threat is it? We'll ask Col. Randy Larsen, founding director of the Institute for Homeland Security.

And, why are Republicans so upset with Bush's nomination of Harriet Miers (search) for the Supreme Court? We'll get a fair and balanced debate from Democratic attorney Julian Epstein and Republican attorney Chris Horner.

Plus, crews battling a 6,000-acre wildfire scramble to burn off heavy brush near homes Thursday before a resurgence of the hot, dry Santa Ana winds. The blaze threatens about 100 homes in a sparsely populated area about 60 miles east of Los Angeles. We'll have the latest.

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

Veteran newscaster John Gibson gets to the core of the most salient issues facing America today as host of FNC's hard-hitting primetime show "The Big Story with John Gibson."

Airing Monday through Friday at 5 p.m. ET, "The Big Story" gives you expert legal analysis from Judge Andrew Napolitano.

"The Big Story with John Gibson" is one of the reasons that FOX News Channel is the most watched news network in daytime.

Note: All guests and topics subject to change