Watch "The Big Story" weekdays at 5 p.m. ET

FEMA Director Michael Brown has been removed from Hurricane Katrina relief duties in the Gulf Coast and sent back to Washington. Support for Brown has quickly faded over the past few days, but, just last week, President Bush publicly praised him. We'll get reaction from Sen. Kay Bailey Hutchison, R-Texas.

The lost kids of Katrina. With many now orphaned, what will happen to them? We'll ask Nancy McBride, national safety director for the National Center for Missing and Exploited Children.

Then, Louisiana's legal system is in serious jeopardy after Hurricane Katrina. Files, records and evidence that could clear or convict suspects have been washed away or destroyed. Will murderers walk free? We'll get legal insight from Judge Andrew Napolitano, FOX News' senior judicial analyst.

And, four deaths along the Gulf Coast — blamed on a bacterial infection — got a lot of people worried. But the feds say those cases were rare and that a deadly epidemic — like cholera or typhoid — is "very unlikely." But isn't the water in New Orleans toxic? Dr. Manny Alvarez, FOX News medical contributor, weighs in.

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

Veteran newscaster John Gibson gets to the core of the most salient issues facing America today as host of FNC's hard-hitting primetime show "The Big Story with John Gibson."

Airing Monday through Friday at 5 p.m. ET, "The Big Story" gives you expert legal analysis from Judge Andrew Napolitano.

"The Big Story with John Gibson" is one of the reasons that FOX News Channel is the most watched news network in daytime.

Note: All guests and topics subject to change