Watch "Hannity & Colmes" weeknights at 9 p.m. ET!

It’s a special edition of “Hannity and Colmes,” as Sean Hannity reports LIVE from outside Midland on the plains of west Texas, while Alan Colmes holds down the fort in New York.

For three nights this week we'll be reporting on the critical issue of illegal immigration from the frontlines of Texas.

Tonight, illegals are streaming into our country at an alarming rate, but how are they doing it? Who's helping them? And where are they ultimately headed? We’ll show you Sean’s exclusive patrol along the border with Minutemen (search) leader Chris Simcox.

Plus, the billion-dollar narcotics market reigns terror over a small Texas town as two Mexican cartels fight for control of Nuevo Laredo (search). Just how much does drug smuggling affect the region? Find out when we take you to one of the most dangerous border towns tonight.

And, we'll ask Don Goldwater, nephew of Arizona political icon Barry Goldwater (search), what he plans to do about the border disorder now that he's thrown his hat into the ring and announced he will run for governor of that state.

Then, the Israeli army evacuated Jewish settlers from their Gaza (search) homes today, but will their withdrawal end Israel’s occupation of the region? We’ll debate it with G. Gordon Liddy.

Also, with the deadline looming for authorities to release the prime suspect in the disappearance of Natalee Holloway (search), does her family feel that real progress has been made in the case? We'll get reaction from Natalee's father, Dave Holloway.

These stories and much more... Don't miss YOUR chance to join the debate tonight!

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

Fast-paced and hard-hitting, "Hannity & Colmes" brings viewers a heated discussion in a nightly face-off. Relishing in controversial topics, personalities and social issues, conservative radio commentator Sean Hannity and liberal radio personality Alan Colmes offer their points-of-view in an often animated, always compelling debate.

But, unlike similar debate shows — which often appear scripted — "Hannity & Colmes" conducts a live, spur of the moment deliberation on politics and social topics. Also, differentiating the show is its dedication to "move away from the Beltway," bringing audiences an alternative discussion program without the "in" comments.

Adding fuel to the fire, several high-profile guests have joined the program on a wide-range of topics.

"With guests who are 'in the middle of the fight,' we're able to hear their point-of-view on the topics, as well as advance our own feelings," said Hannity.

"Believe it or not, I agree with that statement," quipped Colmes.