Watch "Hannity & Colmes" weeknights at 9 p.m. ET!

It’s a special edition of “Hannity and Colmes,” as Sean Hannity reports live from outside Midland on the plains of west Texas, while Alan Colmes holds down the fort in New York.

For the next three nights, we'll be reporting on the critical issue of illegal immigration from the frontlines of Texas.

Tonight, we’ll show you exclusive training video from the Minutemen’s staging grounds as they prepare to patrol the Texas border. Plus, we’ll talk with the Minuteman organizer Chris Simcox.

For more on the problems at our borders, we’ll also talk with Congressmen J.D. Hayworth (R-AZ) and Mike Conway (R-TX).

What really happened the night Natalee Holloway (search) vanished in Aruba? We have new details on a key witness.

And then, after a Connecticut groom vanished on his honeymoon, we'll examine the evidence with famed forensic pathologist Dr. Henry Lee.

Plus, are Democrats ready to stand behind President Bush's Supreme Court (search) pick or will they try to derail the nomination? Radio talk show host Michael Reagan and FNC political analyst and Democratic strategist Mary Anne Marsh join us for a heated debate.

These stories and much more... Don't miss YOUR chance to join the debate tonight!

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

Fast-paced and hard-hitting, "Hannity & Colmes" brings viewers a heated discussion in a nightly face-off. Relishing in controversial topics, personalities and social issues, conservative radio commentator Sean Hannity and liberal radio personality Alan Colmes offer their points-of-view in an often animated, always compelling debate.

But, unlike similar debate shows — which often appear scripted — "Hannity & Colmes" conducts a live, spur of the moment deliberation on politics and social topics. Also, differentiating the show is its dedication to "move away from the Beltway," bringing audiences an alternative discussion program without the "in" comments.

Adding fuel to the fire, several high-profile guests have joined the program on a wide-range of topics.

"With guests who are 'in the middle of the fight,' we're able to hear their point-of-view on the topics, as well as advance our own feelings," said Hannity.

"Believe it or not, I agree with that statement," quipped Colmes.