Watch "Hannity & Colmes" weeknights at 9 p.m. ET!

Here's just some of what we've got planned for you on a special edition of "Hannity & Colmes" tonight!

Authorities continue to search for convicted robber George Hyatte (search) and his wife, who officials say shot and killed a corrections officer outside a Tennessee courthouse. We'll get an update on the nationwide manhunt from Jennifer Johnson of the Tennessee Bureau of Investigations (search).

Then, Westchester County D.A Jeanine Pirro (search) officially tossed her hat into the ring and launched her bid for the U.S. Senate, seeking to unseat Senator Hillary Clinton (search). “I'm not looking to bloody up Hillary, of course 60 percent of New Yorkers just want to know if she is going to fill out her term.” Is the former First Lady ready to don the gloves and fight the hard-hitting Republican? We’ll ask former Clinton advisor Dick Morris.

Plus, a pro-family organization withdraws its support for Supreme Court (search) nominee John Roberts' (search) confirmation because of his work helping overturn a Colorado referendum on gays. How will other conservative groups react? And will this weekend’s "Justice Sunday II" (search) evangelical rally garner enough conservative Christian support for remaking the court? Former Senator Zell Miller (D-GA) weighs in.

And, lawyers for Dutch suspect Joran van der Sloot (search) were back in court appealing an earlier decision by the judge in the case to allow the FBI to review documents involved in the Natalee Holloway (search) investigation. Find out what van der Sloot is telling authorities about the night Natalee disappeared, and why police need to put the pressure on him NOW! Natalee's father, Dave Holloway, joins us.

Also, we'll take you to New Jersey where republican towns are being left without terrorism funding because they are republicans! You won't believe this exclusive video!

These stories and much more... Don't miss YOUR chance to join the debate tonight!

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

—The Associated Press contributed to this story.

About the Show

Fast-paced and hard-hitting, "Hannity & Colmes" brings viewers a heated discussion in a nightly face-off. Relishing in controversial topics, personalities and social issues, conservative radio commentator Sean Hannity and liberal radio personality Alan Colmes offer their points-of-view in an often animated, always compelling debate.

But, unlike similar debate shows — which often appear scripted — "Hannity & Colmes" conducts a live, spur of the moment deliberation on politics and social topics. Also, differentiating the show is its dedication to "move away from the Beltway," bringing audiences an alternative discussion program without the "in" comments.

Adding fuel to the fire, several high-profile guests have joined the program on a wide-range of topics.

"With guests who are 'in the middle of the fight,' we're able to hear their point-of-view on the topics, as well as advance our own feelings," said Hannity.

"Believe it or not, I agree with that statement," quipped Colmes.