Here's what is on tap for Wednesday:

"FOX & Friends First"
Starts at 6 a.m. ET

The investigation into who is responsible for the London terror attacks. Intelligence analyst Christina Corbett lays out the very latest leads.

Plus, Aruban judges in the Natalee Holloway (search) case are set to decide if the Kalpoe brothers should go back to jail and if Joran van der Sloot walks free. We'll get reaction from Jossy Mansur, editor in chief of Diario, Aruba's largest daily newspaper.

"FOX & Friends"
Starts at 7 a.m. ET

Eileen Collins, the first woman to pilot a space shuttle and the first female commander, will preside over NASA's return to space more than two years after the Columbia tragedy. We'll be joined by Eileen's husband, Pat Youngs, from the Kennedy Space Center.

Plus, we'll preview what is sure to be an emotional launch with Doug Brown, whose brother, astronaut David Brown, perished in the Columbia tragedy.

We'll get the legal lowdown on key motions expected in the Natalee Holloway case from FOX News legal analyst, Peter Johnson Jr.

And, we'll get a preview of "Minding the Store," from comedian Pauly Shore!

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

This offbeat morning show features anchors E.D. Hill, Steve Doocy and Brian Kilmeade. They take a look at the day's news, sports and weather from a different perspective. It is an interactive show where you can call in to voice your opinion or have your e-mail read. Anything can happen and usually does!

Every day, syndicated radio host and FOX contributor Mancow joins the show with unique insights and commentary on the day's news events, bringing his own brand of offbeat and irreverent humor from his WKQX studio in Chicago.

Plus, now you can watch America's No. 1 cable news morning show seven days a week, as hosts Juliet Huddy, Julian Phillips and Mike Jerrick man the morning show ship on the weekends!

There's no telling what "FOX & Friends" will be cooking up outside our Manhattan studios on 6th Avenue. So, if you are in New York, drop by — the Morning Crew loves an audience! We are located at: 1211 Avenue of the Americas, between 47th and 48th streets.

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- Note: Guests and topics subject to change. FOX News does not endorse content on external sites.