Guests and Topics: Wednesday, June 22

See you weeknights in the No Spin Zone at 8 p.m. and 11 p.m. ET!

Tonight ... "The O'Reilly Factor" is on...

The heat is on! Is the prime suspect in the Natalee Holloway (search) mystery close to cracking? How is Joran van der Sloot's (search) changing story effecting the investigation? We’ve got the very latest on this developing saga. Plus, 'On the Record's' Greta van Susteren orchestrates a tête-à-tête between Natalee’s mom, Beth Twitty (search), and Joran’s dad, Paul van der Sloot (search). She’ll tell us how she brokered the talks and what the parents had to say to each other.

Plus, why are two former writers for the Indianapolis Star (search) suing the paper? Editorialists James Patterson and Lisa Coffey are on-hand to discuss why they believe there is anti-Christian bias in the media.

And, author Damali Ayo stops by to talk about his new book, “How To Rent a Negro.” Controversial? You bet.

Then, Clifford in the doghouse? Sesame Street on poverty row? Bill Moyers (search) mouths off at Republicans for fiscal cuts to public TV. Is the whole fight over PBS (search) just political b.s? Bill gets the answers tonight on the “Factor.”

This story and much more including a brand-new edition of our world famous "Talking Points Memo" and "The Most Ridiculous Item of the Day"! Don't miss tonight's explosive edition of "The O'Reilly Factor"!

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

"Other interview news shows are guest-driven," says Emmy award-winning broadcast journalist Bill O'Reilly. "'The O'Reilly Factor' is driven by me. I will not stand for 'spin.' I look for guests who will stand up and verbally battle for what they believe in."

"The O'Reilly Factor" uncovers news items from the established wisdom and goes against the grain of the more traditional interview-style programs. O'Reilly's signature "No Spin Zone" cuts through the rhetoric as he interviews the players who make the story newsworthy.

Pushing beyond just the headlines, "The O'Reilly Factor" also features issues from local markets that do not find the national spotlight on other newscasts. According to O'Reilly, "Just because a story originates from somewhere the networks typically avoid, doesn't mean it contains less challenging issues, or compelling ideas."

See you in the No Spin Zone, tonight at 8 p.m. and 11 p.m. ET!

— All topics and guests subject to change.

—The Associated Press contributed to this report.