Oprah Winfrey's (search) La Perla sweats — and the rest of her self-described "classic, fun and relaxed" look — has earned her a spot on the Vanity Fair best-dressed list (search) for a second year in a row.

"The key to elegance is not just wearing beautiful things but making what you're wearing come alive," she tells the magazine for its April issue.

Also on the list again are Sofia Coppola, Kate Moss, Queen Rania of Jordan and actress Sienna Miller (search).

Miller says her style is "a little Gypsyish." Edie Sedgwick is her fashion icon and she picks Jimi Hendrix, Jim Morrison and fiance Jude Law (search) as the most stylish men.

Law, who says he looks like a "messy schoolteacher," also made the list, along with Andre 3000, newscaster Anderson Cooper, who is a son of Gloria Vanderbilt, musician Charlie Watts and director Wes Anderson.

George Clooney's (search) signature look is "no tie, collar open, beautiful suit," and he says his favorite shoes are Tod's. He's also on the list for a second time.