MTV's Ozzie and Harriet, Jessica Simpson and Nick Lachey (search), are about to enter either network stardom or infamy.

With ABC's "The Nick & Jessica Variety Hour" - an homage to decades-gone family shows like "The Sonny and Cher Comedy Hour" and "Donny and Marie" (search) - America's cable sweethearts seem poised to break out of their teeny-bopper cable universe and into tens of millions of living rooms.

The young married couple, who've ridden a wave of popularity since their MTV show, "Newlyweds," (search) became a hit last year, will mix it up with an assortment of stars, including Mr. T., The Muppets (search) and singers Jewel, Babyface, Kenny Rogers (search), and even baseball Hall of Famer Johnny Bench.

The show, Sunday at 9 p.m., is a throwback to variety programs from the 1970s, when a huge cross section of stars from the worlds of music, comedy and sports would appear in weekly sketches with regulars like the Osmonds.

Then again, as beloved as those old shows were, they sometimes boasted a cheese factor big enough to top a million pizzas.

On "Nick & Jessica" look for comedy sketches that include Jessica as the president and Kermit the Frog and Miss Piggy (search) taping their own variety show.

Musical performances will include a duet with Simpson and Jewel, who is slated to sing, "Who Will Save Your Soul," a Simpson duet with Rogers doing "Islands in the Stream," and a duet with Lachey and Babyface singing Stevie Wonder's (search) "For Once in My Life."

Simpson is also set to perform her new single, "Take My Breath Away," and Bench - Lachey's baseball hero - appears on the show to give the married couple batting tips.

Nick and Jessica end the show with an homage to "Sonny & Cher" when they sing "I've Got You Babe."

The show was taped over two days early last month.

Most of the comedy sketches were done on a closed set, while the musical performances were taped in front of a live audience.

Simpson is taping her own yet-to-be-titled sitcom pilot for ABC this week, and Lachey has been cast as a regular on another new untitled ABC sitcom pilot.