Today on Special Report...

At least 27 people killed and more than 450 wounded as two trucks packed with explosives blow up in Istanbul (search), Turkey.

President Bush and British Prime Minister Tony Blair offer their condolences and vow to continue their fight against global terrorism.

Officers and hundreds of demonstrators clash near the site of talks in Miami to create a free trade zone (search) for North and South America.

A bomb explodes at the offices of a U.S.-allied Kurdish political party in Baghdad, killing five people and wounding 40, including children.

Details on those stories and more on Special Report with Brit Hume at 6 p.m. ET.

— Guests and topics are subject to change