| Week 1 | 8/318/318/318/318/31 | vs. Syracuse | TBA | |
| Week 2 | 9/079/079/079/079/07 | vs. Eastern Mich | TBA | |
| Week 3 | 9/149/149/149/149/14 | vs. UCF | 6:00 PM ET5:00 PM CT4:00 PM MT3:00 PM PT11:00 PM GMT | Big Ten Network |
| Week 4 | 9/219/219/219/219/21 | vs. Kent State | TBA | |
| Week 5 | 9/289/289/289/289/28 | Open | | |
| Week 6 | 10/0510/0510/0510/0510/05 | at Indiana | TBA | |
| Week 7 | 10/1210/1210/1210/1210/12 | vs. Michigan | 5:00 PM ET4:00 PM CT3:00 PM MT2:00 PM PT10:00 PM GMT | ESPN or ESPN 2 |
| Week 8 | 10/1910/1910/1910/1910/19 | Open | | |
| Week 9 | 10/2610/2610/2610/2610/27 | at Ohio State | 8:00 PM ET7:00 PM CT6:00 PM MT5:00 PM PT1:00 AM GMT | ABC, ESPN or ESPN 2 |
| Week 10 | 11/0211/0211/0211/0211/02 | vs. Illinois | TBA | |
| Week 11 | 11/0911/0911/0911/0911/09 | at Minnesota | TBA | |
| Week 12 | 11/1611/1611/1611/1611/16 | vs. Purdue | TBA | |
| Week 13 | 11/2311/2311/2311/2311/23 | vs. Nebraska | TBA | |
| Week 14 | 11/3011/3011/3011/3011/30 | at Wisconsin | TBA | |
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