TAMPA, Fla. (AP) -- Quinton Flowers threw for 280 yards and four touchdowns and No. 22 South Florida returned from a Hurricane Irma-imposed layoff to rout Illinois 47-23 on Friday night.
Flowers moved ahead of Matt Grothe and B.J. Daniels into second place on USF's career touchdown pass list with 53. The 2016 American Athletic Conference offensive player of the year also scored his 32nd rushing touchdown, tying Marlon Mack's school record.
The Bulls (3-0) beat a Big Ten opponent for the first time on a night USF honored first responders who worked the past week to help victims of the massive storm that impacted the entire state of Florida.
Illinois (2-1) stumbled in what also was a homecoming of sorts for coach Lovie Smith, who returned to the stadium where he led the Tampa Bay Buccaneers for two seasons before being fired and accepting the challenge of rebuilding the Illini.
Illini freshman Mike Epstein scored on a 46-yard run and a 21-yard pass from Jeff George Jr., who replaced starter Chayce Crouch in the second half.
Flowers completed 15 of 25 passes, including TD throws of 39 yards to Deangelo Antoine, 17 yards to Marquez Valdes-Scantling, 17 yards to D'Ernest Johnson and 13 yards to Tyre McCants. Flowers also scored on a 6-yard run on the last play of the first half and finished with a team-best 106 of USF's 376 yards rushing.
Johnson and Darius Tice joined Flowers in topping 100 yards rushing, with USF amassing 680 yards total offense to Illinois' 354.
Illinois: Played like a young team that will struggle against strong competition. The Illini committed 12 penalties for 110 yards in the first half alone -- embarrassing, unless you consider USF was even worse up to that point with 14 penalties for 115 yards. Epstein continues to be a reason to feel good about the program's future, finishing with 56 yards rushing, 27 receiving and two TDs.
South Florida: Despite being 3-0, the Bulls have yet to play a complete game. They've hurt themselves with penalties and breakdowns on special teams in every game, and once again the offense had difficulty finishing drives early. With Flowers accounting for 81 yards, the Bulls outgained the Illini 184-21 in the opening quarter, yet USF only led 9-2. Illinois kept it close by blocking a field goal, turning another block into a defensive extra point and intercepting Flowers in the end zone.
USF provided first responders who attended the game up to four free tickets apiece. Coach Charlie Strong also offered every high school team in the state free admission to the nationally televised game.
The school said more than 80 prep teams, many of them idle because their games were canceled because of Hurricane Irma, accepted the invitation.
USF began the season ranked 19th and slipped three spots after having to overcome slow starts to beat San Jose State on the road and Stony Brook at home. Illinois might be the best of the teams they've faced but a less-than-sharp performance against the Illini likely won't do much to improve their position.
Illinois: Off next week before the Big Ten opener at home against Nebraska on Sept. 29.
South Florida: Remain home for the American Athletic Conference opener against Temple on Thursday night.