NEW ENGLAND (7-2) at SAN FRANCISCO (1-8)

Sunday, 4:25 p.m. ET, CBS

OPENING LINE - Patriots by 14

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RECORD VS. SPREAD - New England 7-2, San Francisco 2-7

SERIES RECORD - 49ers lead 8-4

LAST MEETING - 49ers beat Patriots 41-34, Dec. 16, 2012

LAST WEEK - Patriots lost to Seahawks 31-24; 49ers lost to Cardinals 23-20

AP PRO32 RANKING - Patriots No. 3, 49ers No. 31

PATRIOTS OFFENSE - OVERALL (8T), RUSH (13), PASS (8).

PATRIOTS DEFENSE - OVERALL (18), RUSH (14), PASS (19).

49ERS OFFENSE - OVERALL (29), RUSH (7), PASS (30).

49ERS DEFENSE - OVERALL (32), RUSH (32), PASS (14).

STREAKS, STATS AND NOTES - Patriots only road win vs. 49ers came in 2008 with Matt Cassel at QB. Tom Brady, who grew up in Bay Area, has never played at San Francisco. ... With win, Brady ties Brett Favre for second most for QB with 199. Peyton Manning holds record with 200. ... New England opened season with record 258 straight passes without INT until Brady threw one vs. Seattle last week. Brady missed first four games this season while suspended. ... Win would assure Patriots of 16th straight non-losing season. ... New England RB LeGarrette Blount has 12 TDs on ground, two shy of Curtis Martin's franchise record. ... Niners have lost eight straight games, one shy of franchise worst set in 1978. ... San Francisco QB Colin Kaepernick threw four TD passes in only meeting vs. Pats in 2012, season 49ers went to Super Bowl. ... 49ers K Phil Dawson needs one FG to become 10th in NFL with 400 for career. ... San Francisco had allowed 100-yard rusher in NFL record seven straight games before holding David Johnson to 55 yards and Arizona to 80 total last week. ... Fantasy Tip: Patriots TE Martellus Bennett coming off third 100-yard game of season and could be in for another big day with Rob Gronkowski nursing injury and listed as out for the game on Friday's injury report.

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AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL