SAN FRANCISCO (1-7) at ARIZONA (3-4-1)

Sunday, 4:25 p.m. ET, Fox

OPENING LINE - Cardinals by 11 +

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RECORD VS. SPREAD - 49ers 1-7,Cardinals 3-5

SERIES RECORD - 49ers lead 29-21

LAST MEETING - Cardinals won 33-21, Oct. 6

LAST WEEK - 49ers lost to Saints 41-23, Cardinals had bye, lost to Panthers 30-20 on Oct. 30

AP PRO32 RANKING - 49ers No. 31, Cardinals No. 20

49ERS OFFENSE - OVERALL (29), RUSH (5), PASS (31)

49ERS DEFENSE - OVERALL (32), RUSH (32), PASS (11)

CARDINALS OFFENSE - OVERALL (10), RUSH (13), PASS (11)

CARDINALS DEFENSE - OVERALL (1), RUSH (16), PASS (3)

NOTES, STREAKS, STATS AND NOTES: Chip Kelly's college teams at Oregon lost seven games in four seasons; his 49ers have lost seven in row. ... San Francisco's losing streak is its longest since dropping eight straight in 2007. ... 49ers gained 486 yards last week vs. New Orleans, most for franchise in three seasons ... QB Colin Kaepernick's 393 yards passing against Saints second most of his career. 393 yards passing more than double San Francisco's season average (190.4). ... 49ers' Phil Dawson needs three field goals to be 10th kicker to reach 400 in career. ...Last year, Cardinals'47-7 home win over San Francisco was largest point differential in series history. ... Cardinals intercepted Kaepernick four times in that game, returning two for TDs. ... Arizona sacked then-starting QB Blaine Gabbert seven times in win at San Francisco this season. ... Arizona RB David Johnson leads NFL in yards from scrimmage (1,112). ... QB Carson Palmer's 363 yards passing vs. Carolina his most of season but he was sacked eight times. ... Cardinals WR Larry Fitzgerald has more TD catches against 49ers (16) than any other player in NFL history. Fitzgerald only active player with 16 TDs against one team. He also has 16 vs. Rams. ... Fantasy Tip: Johnson again. NFC offensive player of October has 21 TDs in his first 24 NFL games, eight this season. 49ers are last in NFL in total defense and rush defense and have allowed 31 TDs, tied for 31st.

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