NEW ORLEANS (3-4) at SAN FRANCISCO (1-6)

Sunday, 4:05 p.m. ET, Fox

OPENING LINE - Saints by 2

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RECORD VS. SPREAD - New Orleans 5-2, San Francisco 1-6

SERIES RECORD - 49ers lead 48-25-2

LAST MEETING - 49ers beat Saints 27-24, OT, Nov. 9, 2014

LAST WEEK - Saints beat Seahawks 25-20; 49ers had bye, lost to Bucs 34-17 on Oct. 23

AP PRO32 RANKING - Saints No. 21, 49ers No. 31

SAINTS OFFENSE - OVERALL (2), RUSH (25), PASS (1).

SAINTS DEFENSE - OVERALL (28), RUSH (18), PASS (29).

49ERS OFFENSE - OVERALL (32), RUSH (4), PASS (32).

49ERS DEFENSE - OVERALL (30), RUSH (32), PASS (7).

STREAKS, STATS AND NOTES - Saints won seven of past nine regular-season meetings in series. ... New Orleans has won three of four following 0-3 start. ... Saints QB Drew Brees seeks fourth straight game with passer rating of at least 100. Brees needs four TD passes to join Peyton Manning and Brett Favre as only players with 450 in NFL history. ... New Orleans WR Brandin Cooks looks for fourth straight game with TD catch. ... Saints allowed three points on opponent's opening drive all season. ... San Francisco QB Colin Kaepernick completed fewer than half his passes in both starts this season and is 46 percent since taking over from Blaine Gabbert. ... Kaepernick averages 8.8 yards per carry. ... San Francisco averages league-low 4.9 yards per play. ... 49ers LB Ahmad Brooks has 4 1/2 sacks, two forced fumbles, two INTs in four career games vs. Saints. ... San Francisco has league-low 31 penalties. ... Fantasy Tip: Saints RB Tim Hightower rushed for 102 yards last week and faces league's worst run defense that has allowed 100-yard rusher in six straight games.

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AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL