INDIANAPOLIS (2-4) at TENNESSEE TITANS (3-3)

Sunday, 1 p.m. EDT, CBS

OPENING LINE - Pick-em

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RECORD VS. SPREAD - Indianapolis 2-3-1, Tennessee 2-4

SERIES RECORD - Colts lead 29-14

LAST MEETING - Colts beat Titans 30-24, Jan. 3, 2016

LAST WEEK - Colts lost to Texans 26-23, OT; Titans beat Browns 28-26

AP PRO32 RANKING - Colts No. 27, Titans No. 21

COLTS OFFENSE - OVERALL (13), RUSH (17), PASS (13).

COLTS DEFENSE - OVERALL (30), RUSH (24), PASS (29).

TITANS OFFENSE - OVERALL (11), RUSH (3), PASS (29).

TITANS DEFENSE - OVERALL (9), RUSH (7), PASS (11).

STREAKS, STATS AND NOTES - Colts have won nine straight and 14 of last 15 in series. QB Andrew Luck is 7-0 as starter vs. Titans and 4-0 in Tennessee. ... Colts blew 14-point lead in fourth quarter in losing last game. ... Colts have scored most points of any AFC South team and allowed most points in division. ... Luck has been sacked NFL-worst 23 times. ... RB Frank Gore has four TDs rushing in two games at Titans. Gore ranks ninth in NFL history with 12,474 rushing yards, including 106 yards last week. . WR T.Y. Hilton had four catches for 94 yards in last game at Tennessee. Hilton has 28 catches for 436 yards and three TDs in past four games. ... LB Erik Walden has three sacks and two forced fumbles in past four games. ... K Adam Vinatieri has made 41 consecutive field goals, second-longest streak in NFL history. ... Titans have not won three straight since Weeks 2-4 of 2011 season. ... Titans QB Marcus Mariota has thrown for three TDs in consecutive games and posted 132.6 passer rating that was third highest of his career. ... WR Kendall Wright had eight catches for 133 yards last week, second-best game of career. ... RB DeMarco Murray ranks second in NFL with 698 yards from scrimmage and is averaging 98.8 yards rushing per game over past four outings. ... Titans had six sacks in consecutive games for first time since 2010. ... LB Brian Orakpo has sack in five straight games, with seven for season to match his 2015 total. ... WR Andre Johnson, who played with Colts last season, has 57 catches for 839 yards and seven TDs in past seven games vs. Colts. ... Titans have allowed 91 yards rushing over past two games. ... TE Delanie Walker will play 150th game of career Sunday. ... Fantasy Tip: Mariota has thrown six TD passes in past two games and run for at least 60 yards in each. He threw for 367 yards and two TDs as rookie in only start vs. Colts.

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AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL