GREEN BAY, Wis. (AP) Pass-rushing linebacker Clay Matthews will miss the Green Bay Packers' game on Sunday against Detroit because of ankle and hamstring injuries.

The Packers downgraded Matthews' status for the home opener from questionable to out after practice Saturday. Matthews has not practiced all week.

Green Bay also will be without Morgan Burnett after the starting safety was ruled out on Saturday with a groin injury.

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Two other key defensive players with knee injuries were downgraded from questionable to doubtful on Saturday: defensive tackle Letroy Guion and defensive end/linebacker Datone Jones.

Top cornerback Sam Shields (concussion) has already been ruled out for a second straight game.

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AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL