Ryan Mathews is unlikely to play in Week 11. Eric Hartline USA TODAY Sports

Philadelphia Eagles running back Ryan Mathews missed practice again on Wednesday, and according to head coach Chip Kelly, he remains in the NFL's concussion protocol after leaving Week 10's game with a concussion.

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Mathews' inability to practice and advance through the concussion's protocol on Wednesday paints a grim picture for his chances of playing in Week 11. Stay tuned for more updates as the week progresses on.