Mariota is dealing with a knee injury.

Christopher Hanewinckel USA TODAY Sports

Tennessee quarterback Marcus Mariota will miss his second straight game, with the Titans ruling him out against the Houston Texans. Zach Mettenberger will start in his place again.

Titans coach Ken Whisenhunt said Friday that Mariota made progress this week. The rookie practiced in a limited fashion each day, but Whisenhunt says Mariota isn't ready yet after spraining his left knee on Oct. 18.

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Mettenberger threw for 187 yards and a touchdown last week in a 10-7 loss to Atlanta. The second-year quarterback is 0-7 as a starter.

The Titans also ruled out cornerback Perrish Cox (hamstring) and wide receiver Harry Douglas (ribs) for a second straight game.