SAN FRANCISCO (1-0) at PITTSBURGH (0-1)

Sunday, 1 p.m. ET, Fox

OPENING LINE - Steelers by 7

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RECORD VS. SPREAD - 49ers 1-0, Steelers 0-0-1

SERIES RECORD - 49ers lead 11-9

LAST MEETING - 49ers beat Steelers 20-3, Dec. 19, 2011

LAST WEEK - 49ers beat Vikings 20-3; Steelers lost to Patriots 28-21

AP PRO32 RANKING - 49ers No. 19, Steelers No. 12

49ERS OFFENSE - OVERALL (T10), RUSH (1), PASS (29).

49ERS DEFENSE - OVERALL (4), RUSH (7), PASS (6).

STEELERS OFFENSE - OVERALL (2), RUSH (6), PASS (5).

STEELERS DEFENSE - OVERALL (21), RUSH (T11), PASS (24).

STREAKS, STATS AND NOTES - Teams have split last four meetings. ... San Francisco coach Jim Tomsula is Pittsburgh native whose grandfather owned restaurant near Forbes Field, former home of Steelers and baseball's Pirates. ... 49ers RB Carlos Hyde's 168 yards in opener were most by San Francisco back in first start since 1970. ... San Francisco QB Colin Kaepernick is 18-7 in first 25 starts, fifth-best mark in NFL history. ... Steelers are 7-1 in home openers under head coach Mike Tomlin. ...Pittsburgh WR Antonio Brown has caught at least five passes and gained 50 yards receiving in 33 straight games. Brown needs one reception to become fourth player in team history to reach 400 career catches. ... Steelers RB DeAngelo Williams ran for 127 yards against New England, his first 100-yard game since Sept. 22, 2013. Steelers starting RB Le'Veon Bell serves last game of two-game suspension Sunday. ... Pittsburgh is 61-30-1 at Heinz Field since it opened in 2001, third-best mark in the league. ... Fantasy: 49ers WR Anquan Boldin has 44 receptions for 626 yards and four TDs in seven career games against Steelers; Roethlisberger is 16-4 at home against NFC, throwing for 33 touchdowns against 12 interceptions.

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AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL