HOUSTON (AP) Collin McHugh went 7 2-3 innings and Hank Conger hit a grand slam as the Houston Astros beat the Minnesota Twins 8-0 on Friday night.

McHugh (15-7) gave up seven hits and struck out six in picking up his second straight win. McHugh has allowed two runs or fewer in each of his last six starts.

Colby Rasmus had two hits, including a monstrous two-run homer into the upper deck in right field in the second inning to give the Astros a 3-0 lead.

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Conger upped the lead to 7-0 with the grand slam in the fourth into the Crawford Boxes in left field. After Evan Gattis, Jed Lowrie and Carlos Gomez led off the inning with singles, Mike Pelfrey (6-9) struck out the next two hitters to set up Conger's second grand slam of the season.

Conger, who had not hit a grand slam before this season, hit his first career grand slam Aug. 1, against Arizona. He added an RBI single in the eighth.

Carlos Correa's RBI fielder's choice in the first gave Houston a 1-0 lead.

Lowrie had three hits and scored twice, and Gattis had two hits for Houston.

Pelfrey was tagged for seven runs and eight hits with five strikeouts in four innings. It was Pelfrey's second straight outing of four innings or less - both against the Astros. Pelfrey lasted just 3 2-3 innings in his last start against the Astros on Saturday, allowing four runs in a 4-1 loss.

Joe Mauer had two hits and the best chance to score for Minnesota but was thrown out at home by Gomez trying to score on Miguel Sano's single in the first. The Twins did not get a runner past second base the rest of the way.

TRAINER'S ROOM

Twins: RHP Phil Hughes (lower back inflammation) is expected to throw off a mound in Minneapolis this weekend and will join the club in Kansas City for a simulated game next week.

Astros: OF George Springer was activated from the 15-day DL on Friday and started in right field. Springer went on the DL with a right wrist fracture on July 2. He went 1 for 4 with a single.

TEN ASTROS WITH TEN HOMERS

The grand slam was Conger's 10th home run of the season, giving the Astros 10 players with 10 or more home runs, breaking the franchise record of nine set in 2000. The major league record is 11 players with 10 or more home runs set by the Detroit Tigers in 2004.

UP NEXT

Twins: RHP Ervin Santana (3-4) goes Saturday in the second game of the three-game series. Santana threw seven shutout innings with 10 strikeouts in his last start Sunday against the Astros.

Astros: RHP Lance McCullers (5-5) matches up for a second straight start against Santana after taking the loss Sunday, giving up three runs in six innings.