CLEVELAND (AP) -- Chris Sale allowed two runs in seven innings and the Chicago White Sox used a five-run first to power past the Cleveland Indians 10-3 on Saturday night.

Sale (9-5) cruised after being handed the big lead before taking the mound. The left-hander struck out seven to regain the American League lead with 170. Sale allowed seven hits and didn't walk a batter.

Jose Abreu drove in three runs, Melky Cabrera was 3 for 5 with two RBIs and Carlos Sanchez hit his first major league homer.

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The White Sox, who came to Cleveland with six losses in seven games, have outscored the Indians 24-4 in winning the first three games of a series that ends Sunday.

Carlos Carrasco (10-8) allowed six runs in four innings. The right-hander hasn't won since coming within one out of pitching a no-hitter against Tampa Bay on July 1.

Chicago had six hits and sent nine to the plate in the first. Abreu and Tyler Flowers each had two-run singles, while Cabrera added an RBI single.

Sanchez hit a solo homer in the fourth. Cabrera, who had three hits, added another RBI single in the seventh. Abreu also singled in a run in the ninth.

Sale allowed a season-high 11 hits in a loss to Kansas City in his last outing, but his teammates gave him plenty of cushion Saturday.

Chicago scored three times before Carrasco retired a batter. Adam Eaton and Tyler Saladino opened the game with singles. After Cabrera's single scored a run, a passed ball by catcher Yan Gomes put runners at second and third. Abreu's single made it 3-0.

Alexei Ramirez doubled with two outs and Flowers, snapping an 0-for-17 skid, singled for two more runs.

Carrasco was hit in the face by Cabrera's first-inning line drive on April 14 at Progressive Field. He was removed from the field on a golf cart, but sustained no serious injuries and missed only one turn in the rotation.