Updated

(SportsNetwork.com) - The Los Angeles Angels of Anaheim attempt to hang an 11th straight loss on the Colorado Rockies Wednesday when the interleague foes wrap up a brief two-game set at Angel Stadium.

Los Angeles added to the Rockies' woes in last night's opener, as Johnny Giavotella drove in the go-ahead run in the eighth inning to lead the Angels to a 5-2 win.

Matt Joyce drove in three runs and Carlos Perez also had an RBI for the Angels, who have won five of their last seven. C.J. Wilson (2-2) tossed eight innings and allowed two runs on five hits with a walk and six strikeouts.

"C.J. was the story tonight," said Angels manager Mike Scioscia. "They have some good bats over there and he was able to maintain his stuff for a solid eight innings. He had great command all night."

Troy Tulowitzki and Corey Dickerson each drove in a run for the Rockies, who are in the midst of their worst stretch since 2005.

The Rockies haven't dropped 11 straight since July 4-17, 2000.

Kyle Kendrick allowed two runs on seven hits while striking out five, and Rafael Betancourt (0-1) took the loss after giving up three runs in the eighth.

"Kyle has pitched very well for us and he did a hell of a job tonight," said Colorado manager Walt Weiss. "It was real tough for us to get anything going tonight."

Heading to the hill for the Rockies on Wednesday will be righty Jordan Lyles, who has lost his last two and three of his past four starts. Lyles fell to the Arizona Diamondbacks last Wednesday, allowing four runs and nine hits in seven innings to drop to 2-3 to go along with a 4.42 ERA.

Lyles is 2-1 in four games (3 starts) versus the Halos with a 5.82 ERA.

As for Los Angeles, it will hand the ball to lefty Hector Santiago, who is 2-2 with a 2.57 ERA. Santiago had his best start of the season on Thursday against Houston, but had nothing to show for it, despite tossing 6 1/3 scoreless innings. He only gave up one hit, but walked four batters in his team's 3-2 loss.

"The last two or three times out have been very good for me," said Santiago, who also balked twice. "I think the soft contact is something that has given me more confidence. Even when they hit the ball, it's not getting laced somewhere in the gap, it's not getting drilled over the wall. It means I've got good stuff and it's working in the zone."

The Angels have beaten Colorado six straight times, but this is the first series between these teams since 2012.