Charleston, SC (SportsNetwork.com) - Second-seeded Russian Ekaterina Makarova was a three-set second-round winner Wednesday at the ladies' Family Circle Cup tennis event.

The left-hander came from behind to beat Chinese Zhang Shuai 5-7, 6-3, 6-2 on the clay courts at Family Circle Tennis Center.

Meanwhile, fourth-seeded former French Open runner-up Sara Errani of Italy dismissed last year's Charleston runner-up Jana Cepelova 6-3, 7-6 (7-5) and Spaniard Lara Arruabarrena upset ninth-seeded 2010 Charleston champion and former U.S. Open titlist Sam Stosur 6-3, 3-6, 6-4.

The Slovakian Cepelova gave way to German Andrea Petkovic in last year's Family Circle finale.

In other action involving seeds, qualifier Danka Kovinic of Montenegro upended No. 12 Swiss teenager Belinda Bencic 4-6, 6-3, 6-2 and No. 13 Romanian Irina- Camelia Begu snuck past Kazakhstan's Yaroslava Shvedova 6-0, 6-7 (4-7), 6-4.

In matches involving unseeded Americans, Madison Brengle whipped Croat Donna Vekic 6-1, 6-3 and Spanish qualifier Sara Sorribes Tormo doused Shelby Rogers 7-5, 6-1.

Also on Day 3, Romanian Andreea Mitu drubbed Croat Ajla Tomljanovic 6-2, 6-2.