Gelsenkirchen, Germany (SportsNetwork.com) - Bayer Leverkusen must pick itself up in time for Saturday's Bundesliga clash at Schalke following a disappointing ending to the club's Champions League run.

Leverkusen brought a 1-0 lead against Atletico Madrid into the second leg of its knockout-round clash with the Spanish club. However, after losing 1-0, the match was ultimately decided on penalty kicks, with Atletico advancing.

Roger Schmidt's men must now rebound this weekend against Schalke in an important match of top-five teams.

Leverkusen enters the fixture in the fourth and final Champions League place, three points clear of Schalke, and having won three straight Bundesliga games.

Schalke, meanwhile, has claimed just one win from its last five games in the league, and defender Joel Matip knows his team must focus on Saturday's result.

"Ultimately you do lots of maths, but for us the most important thing is to focus on ourselves and collect points," Matip said. "On Saturday we host a direct competitor, Bayer Leverkusen, so we are desperate to win and strengthen our situation."

Augsburg is just one point back of Schalke and will be favored to claim three points on Saturday at second-from-the-bottom Freiburg.

Monchengladbach enters the weekend in third place, but the club will travel to leaders Bayern Munich and won't be expecting to take much from that fixture.

Second-place Wolfsburg trails Bayern by 11 points and the club will go for its sixth win in seven Bundesliga games when the team hits the road to face mid- table Mainz.

Borussia Dortmund was bounced from the Champions League by Juventus in midweek and will attempt to rebound with a win over Hannover.

Last-place Stuttgart squares off with Eintracht, Paderborn attempts to snap a four-game losing skid against Hoffenheim and Werder Bremen visits Cologne.

On Friday, Hertha Berlin used an 84th-minute goal from Sebastian Langkamp to claim a 1-0 win at Hamburg, which sits just two points above the relegation places.