C.J. Spiller scored on a 102-yard kickoff return, and rookie receiver Sammy Watkins had a 12-yard touchdown catch in leading the Buffalo Bills to a 29-10 win over the Miami Dolphins on Sunday.
The Dolphins (1-1) also lost a key offseason addition when running back Knowshon Moreno did not return after hurting his left elbow 11 minutes in.
Spiller and Watkins both scored in the third quarter, putting Buffalo ahead 23-10.
Buffalo is 2-0 start for the first time since 2011, and sixth time since 2000.
The Bills rode the momentum of a charged-up crowd in a home opener that celebrated the franchise's past and future.
The Bills paid tribute to late owner Ralph Wilson, who died in March. On Tuesday, Wilson's estate reached a "definitive agreement" to sell the team to Terry and Kim Pegula for an NFL-record $1.4 billion.
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