Bo Wallace threw for 320 yards and a touchdown, and the 15th-ranked Mississippi Rebels opened their Southeastern Conference schedule by routing Vanderbilt 41-3 on Saturday in the league opener for both teams.
The Rebels (2-0) have beaten Vanderbilt in Nashville in consecutive seasons after the Commodores had won five of the previous six. The Rebels won in dominating fashion.
Ole Miss scored on seven of its first eight possessions with the shortest drive covering 67 yards. Jaylen Walton started the scoring with a 20-yard TD, and I'Tavius Mathers and DeVante Kincade also ran for TDs.
Wallace put the Rebels up 20-0 with a 20-yard TD pass to Cody Core, and he was sacked as the first half ended with Ole Miss threatening to score again.
The Commodores (0-2) still are searching for first-year coach Derek Mason's inaugural win, but at least got their first offensive points with a field goal.