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Ramirez slam, Abreu bomb power White Sox to rout of D-Backs

  • Diamondbacks White Sox Baseball-1.jpg

    Arizona Diamondbacks starting pitcher Brandon McCarthy looks on in the dugout after being pulled during the fourth inning of a baseball game against the Chicago White Sox in Chicago, Friday, May 9, 2014. (AP Photo/Paul Beaty) (The Associated Press)

  • Diamondbacks White Sox Baseball-2.jpg

    Chicago White Sox's Jose Abreu watches his solo home run during the seventh inning of a baseball game against the Arizona Diamondbacks in Chicago, Friday, May 9, 2014. (AP Photo/Paul Beaty) (The Associated Press)

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    Arizona Diamondbacks second baseman Aaron Hill misses a single hit by Chicago White Sox's Alejandro De Aza during the sixth inning of a baseball game in Chicago, Friday, May 9, 2014. (AP Photo/Paul Beaty) (The Associated Press)

Alexei Ramirez hit a grand slam to fuel Chicago's seven-run fourth inning and Jose Abreu hit his major league-leading 13th homer and drove in two runs to lead the White Sox to an 8-3 victory over the Arizona Diamondbacks on Friday night.

Abreu was the designated hitter because of a nagging left ankle injury. He went 3 for 4 and leads the AL with 37 RBIs.

Tyler Flowers also homered for the White Sox, who pounded out 15 hits.

Andre Rienzo (3-0) allowed three runs on four hits in 5 2-3 innings.

Brandon McCarthy (1-6) allowed nine hits and seven runs — all in the fourth inning.

Arizona went up 2-0 on Gerardo Parra's two-run homer in the third inning.