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(SportsNetwork.com) - Arizona lefty Wade Miley will try to get Arizona Diamondback pitchers back on their recently successful track Saturday night, when they return to U.S. Cellular Field for the middle game of a three-game weekend series with the Chicago White Sox.

The Diamondbacks were an ugly 8-22 with a 6.34 earned run average to begin the season, but had gone 5-2 with a 2.35 ERA in a recent stretch before losing a 9-3 decision in Friday's series opener.

Chicago has reached double-digits in hits in its last four games, scoring 27 runs and compiling a .340 batting average.

Miley is winless in five starts since defeating Colorado on April 6.

He pitched well in his last start on Sunday in San Diego, but did not factor in the decision after allowing three runs in seven innings in a game the Padres ultimately won, 4-3.

In two preceding starts, Miley had been nicked for 12 runs in 11 innings.

He's 2-1 with a 1.20 ERA in interleague games, but has never faced the White Sox.

Lefty Jose Quintana gets the start for the hosts after a Monday outing in which he allowed a single run and a single hit in seven innings of Chicago's 3-2 win over the crosstown Chicago Cubs in 12 innings.

"He was great," White Sox manager Robin Ventura said. "Q had a little extra life on it."

On Friday, Alexei Ramirez's grand slam highlighted a seven-run fourth inning and the White Sox coasted from there.

Diamondbacks starter Brandon McCarthy (1-6) was perfect through three innings before giving up nine hits in 10 batters to start the fourth.

Ramirez also tripled for the White Sox, who were coming off a 12-5 loss to the Cubs on Thursday that snapped a season-high four-game winning streak.

Andre Rienzo (3-0) earned the win in 5 2/3 innings after giving up three runs on four hits and two walks with three strikeouts.

White Sox rookie first baseman Jose Abreu batted as the designated hitter because of a sore ankle and had three hits, including his MLB-leading 13th home run.

Gerardo Parra hit a two-run homer for the Diamondbacks, who fell to 4-3 on a nine-game road trip.

McCarthy, coming off his first win of the season on Saturday in San Diego, gave up seven runs on nine hits -- all in the fourth.

This will be the first time these two teams have met since 2011.