Guthrie tries to pitch Royals past Padres

( - Jeremy Guthrie tries to put the brakes on Kansas City's five-game skid on Tuesday when the Royals continue a three-game interleague series against the San Diego Padres at Petco Park.

That may be easier said than done, though, as the Royals have lost all seven games they have ever played in San Diego. That trend continued in Monday's opener, as Jedd Gyorko's ninth-inning homer forced extras and Will Venable's two-run double in the 12th propelled San Diego to a 6-5 win.

The score was tied at 4-4 through 11 innings, but the Royals briefly went in front with a run in the top of the 12th. Salvador Perez roped a one-out double into right-center off Tim Stauffer (1-0), who then fanned Alex Gordon for the second out. Mike Moustakas, who came on as a defensive replacement in the eighth, came through with a single to right, allowing Perez to sprint home just before Chris Denorfia's throw reached the plate.

Louis Coleman started the home half of the 12th for Kansas City and issued a leadoff single to Denorfia. Tim Collins (0-2) took his place on the mound. Alexi Amarista moved Denorfia to second with a sacrifice bunt, Yonder Alonso dropped a single into left in front of a diving Gordon and Venable ended it with a ground-rule double over the wall in right center.

"Honestly, I'm just trying to put the ball in play," said Venable, who enjoyed his fourth career game-winning hit.

Now the Royals will turn to Guthrie to get them back in the win column, as he tries to stop a personal two-game losing streak. Guthrie is 0-2 in four starts since winning his first two outings of the year. He lost to Toronto on Thursday, as he allowed four runs and eight hits in six innings to raise his ERA to 4.50.

Guthrie has faced the Padres three times (2 starts) and is 1-2 with a 5.29 ERA.

San Diego, meanwhile, counters with lefty Robbie Erlin, who hasn't won since April 9. In fact, he's 0-4 with a 7.15 ERA in his last four starts. Erlin's most recent loss came in San Francisco on Wednesday, as he surrendered three runs and eight hits in 6 2/3 innings.

"Definitely not satisfied," Erlin said. "The most important thing is winning, and I didn't give the team a chance to do that. But it's a step in the right direction compared to the last couple outings."