Updated

Cleveland, OH (SportsNetwork.com) - Dayan Viciedo's three-run homer in the ninth inning spoiled Corey Kluber's fantastic start and propelled the Chicago White Sox past the Cleveland Indians, 4-3, to avoid a three-game sweep.

John Axford (0-2) replaced Kluber in the ninth and issued a leadoff walk to Gordon Beckham. Axford struck out rookie slugger Jose Abreu, but walked Adam Dunn to put two runners on. Viciedo then laced a 1-1 fastball over the wall in right to put the White Sox in front.

"I'll chew on it tonight...and be back tomorrow ready to go as if today never happened," Axford said.

Matt Lindstrom stranded a runner on second in the bottom of the ninth to earn his fourth save. Daniel Webb (2-0) earned the win with a scoreless eighth.

Kluber allowed one run on three hits and struck out a career-high 13 in the setback. Kluber set an Indians franchise record with seven straight strikeouts at one point.

"He was sharp," White Sox manager Robin Ventura said of Kluber. "It was a combination of bad swings and swinging at stuff outside the zone."

Andre Rienzo started for the White Sox and allowed three runs on seven hits and four walks over 4 2/3 innings.

Abreu clubbed his major-league leading 12th homer in the first inning to give the White Sox an early 1-0 lead. Kluber left a sinker over the heart of the plate and Cuban rookie sensation roped it over the wall in left-center.

The Tribe pushed a pair of runs across in the third. George Kottaras, in his first at-bat with the Indians, led off with a homer. Kottaras had his contract purchased from Triple-A Columbus on Saturday.

Rienzo retired the next two hitters before giving up a single to Michael Brantley and walking Carlos Santana to put two on. Lonnie Chisenhall blooped a single over third base to score Brantley to make it 2-1.

Kottaras clubbed his second homer in the fourth inning to make it 3-1.

Game Notes

Kottaras was the first Indians player to homer in his first two at-bats with the club ... Kluber is the first Cleveland pitcher to strike out at least 11 batters in consecutive home starts since Dennis Eckersley turned the trick in 1976 ... Chicago was 1-for-4 with runners in scoring position ... The Indians were 1-for-8 with RISP and left 12 runners on base.