Frans Nielsen, Josh Bailey and Ryan Strome scored in the shootout, and the New York Islanders beat the New Jersey 3-2 in what might have been Devils goalie Martin Brodeur's final start.
Devils coach Pete DeBoer hasn't said whether the soon-to-be 42 year-old Brodeur will start the season finale against Boston at home on Sunday.
Brodeur, the NHL career leader in wins (687) and shutouts (124) in a 20-year career with New Jersey, is in the last season of his contract. He won three Stanley Cup titles with the Devils.
Cory Schneider is in line to be the Devils' No. 1 goalie of the future.
Ryan Carter and Patrik Elias scored for the Devils, and Anders Lee and Strome had regulation goals for the Islanders in a matchup of teams that failed to make the playoffs this season.