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Hancock scores 21, Louisville pulls away late to beat Saint Louis 66-51, reach Sweet 16 again

  • NCAA Saint Louis Louisville Basketball-1.jpg

    Louisville guard Chris Jones (3) ande forward Luke Hancock (11) reacts to a call during the second half in a third-round game in the NCAA college basketball tournament against Saint Louis, Saturday, March 22, 2014, in Orlando, Fla. (AP Photo/Phelan M. Ebenhack) (The Associated Press)

  • NCAA Saint Louis Louisville Basketball-2.jpg

    Saint Louis forward Rob Loe (51) shoots over Louisville forward Stephan Van Treese (44) during the second half in a third-round game in the NCAA college basketball tournament Saturday, March 22, 2014, in Orlando, Fla. (AP Photo/Phelan M. Ebenhack) (The Associated Press)

  • NCAA Saint Louis Louisville Basketball-3.jpg

    Louisville coach Rick Pitino, right, yells at guard Russ Smith (2) during the second half in a third-round game in the NCAA college basketball tournament against Saint Louis, Saturday, March 22, 2014, in Orlando, Fla. (AP Photo/Phelan M. Ebenhack) (The Associated Press)

  • NCAA Saint Louis Louisville Basketball-4.jpg

    Louisville forward Luke Hancock (11) goes around Saint Louis center John Manning (54) during the second half in a third-round game in the NCAA college basketball tournament Saturday, March 22, 2014, in Orlando, Fla. (AP Photo/Phelan M. Ebenhack) (The Associated Press)

  • NCAA Saint Louis Louisville Basketball-5.jpg

    Louisville forward Montrezl Harrell (24) aims for the basket as Saint Louis forward Dwayne Evans (21) and center John Manning (54) defend during the second half in a third-round game in the NCAA college basketball tournament Saturday, March 22, 2014, in Orlando, Fla. (AP Photo/Phelan M. Ebenhack) (The Associated Press)

Luke Hancock scored 21 points and defending national champion Louisville shrugged off a cold shooting performance to beat Saint Louis 66-51 on Saturday and advance to the Sweet 16 of the NCAA tournament for the third straight year.

The fourth-seeded Cardinals (31-5) shot under 45 percent, had 19 turnovers and only got 11 points from star Russ Smith. It didn't matter with the fifth-seeded Billikens (27-7) going 0 for 15 from 3-point range and struggling to take care of the basketball.

Louisville moves on the Midwest Regional semifinals in Indianapolis against either No. 1 seed Wichita State or No. 8 seed Kentucky. The unbeaten Shockers and Wildcats meet Sunday in St. Louis.

Saint Louis, which has never been to the Sweet 16, lost in the third round of the tournament for the third consecutive year. Dwayne Evans led the Billikens with 16 points and Atlantic 10 player of the year Jordair Jett finished with 15.