Carlos Santana hit a two-run home run off Tyson Ross, enhancing his chance of opening the season as the Indians' starting third baseman and helping Cleveland beat San Diego 12-7 Wednesday.
Santana is moving from catcher to third base where he is competing with Lonnie Chisenhall for the starting spot. He robbed Chris Denorfia of an extra-base hit with a leaping stab behind the base.
Chisenhall doubled in three trips as the designated hitter to help himself in the competition.
Xavier Nady, who is trying to win a job as the backup to Yonder Alonso at first base, doubled and scored in the fourth inning and tied the game at 4 with a home run off Marc Rzepczynski in the sixth.
Cameron Maybin's bicep injury opens a corner outfield spot for Nady with Will Venable expected to move to center field.