Askia Booker scored all but two of his 18 points during a second-half charge that carried Colorado past Arizona State 61-52 Wednesday night in a game dominated by defense.
Josh Scott added 13 points and 13 rebounds for Colorado (20-7, 9-5 Pac-12), which reached the 20-win mark for the fourth straight season under coach Tad Boyle.
Arizona State (19-7, 8-5) was coming off its biggest home win in school history, a 69-66 double-overtime thriller against then-No. 2 Arizona on Friday night, but the Sun Devils never got into a good rhythm against the Buffaloes.
Colorado improved to 6-5 since losing star point guard and leading scorer Spencer Dinwiddie to a torn ACL on Jan. 12, and the Buffs' second straight 20-win season improved their NCAA tournament profile, although Boyle insists that's not on their minds.
Jahii Carson led Arizona State with 18 points.