James Bell had 17 points and eight rebounds, Ryan Arcidiacono scored 14 points, and No. 6 Villanova won its fifth straight game, 88-62 over DePaul on Saturday.
The Wildcats (16-1, 5-0 Big East) made a whopping 19 of 26 shots (73 percent) in the second half as they continue to steamroll through the revamped conference. Villanova tied a season low with five turnovers.
Daniel Ochefu had 14 points and six rebounds, and Josh Hart hit three 3-pointers and scored 13 points for the Wildcats.
The Blue Demons (10-9, 2-4) entered on a rare two-game conference winning streak, but failed to get three straight for the first time since 2006-07. Brandon Young led them with 13 points.