Per Mertesacker scored on a header off Toni Kroos' cross that gave Germany a 1-0 exhibition victory on Tuesday night that sent England to consecutive home losses for the first time in 36 years.
While Germany deployed a second-string lineup, England used a strong selection. The closest Roy Hodgson's team came to an equalizer was when Andros Townsend struck a post from long range.
England, beaten 2-0 by Chile on Friday, had not lost consecutive matches at Wembley since defeats to Wales and Scotland in 1977.
Germany fans celebrated the win by singing — in English — "Football's coming home" — taken from the England anthem "Three Lions."
It was a miserable way for the English Football Association to round out its 150th anniversary celebrations in front of a crowd of 85,934.