Derek Carr threw for 366 yards and four touchdowns, and Josh Quezada rushed for 105 yards and a score as No. 17 Fresno State defeated Wyoming 48-10 Saturday night.
Fresno State (9-0, 6-0 Mountain West) is one of five Top 25 teams that remain undefeated.
Wyoming (4-5, 2-3) is 0-15 against ranked teams under fifth-year coach Dave Christensen and hasn't beaten a Top 25 team since 2002, when the Cowboys defeated No. 24 Air Force 34-26.
Carr completed 33 of 46 passes with no interceptions before being pulled for the night with 9:45 left and the game well in hand. He has gone 229 pass attempts without an interception.
Quezada had his second consecutive (and second career) 100-yard game on 16 carries.
Brett Smith led the Cowboys, completing 18 of 32 passes for 141 yards and a touchdown. Running back Tedder Easton gained 90 yards.