Updated

BUFFALO (2-2) at CLEVELAND (2-2)

Thursday, 8 p.m. ET, NFL Network.

OPENING LINE — Browns by 3

RECORD VS. SPREAD — Buffalo 3-1, Cleveland 2-2

SERIES RECORD — Browns lead 10-7

LAST MEETING — Bills beat Browns 24-14, Sept. 23, 2012

LAST WEEK — Bills beat Ravens 23-20; Browns beat Bengals 17-6

AP PRO32 RANKING — Bills No. 20; Browns No. 19.

BILLS OFFENSE — OVERALL (16), RUSH (2), PASS (28)

BILLS DEFENSE — OVERALL (27), RUSH (27), PASS (22)

BROWNS OFFENSE — OVERALL (24), RUSH (27), PASS (14)

BROWNS DEFENSE — OVERALL (3), RUSH (4), PASS (9)

STREAKS, STATS AND NOTES — Two surprising teams separated by 194 miles meet for 18th time and third in prime time. ... Bills intercepted Ravens QB Joe Flacco five times last week and lead NFL with nine picks. ... QB EJ Manuel became first rookie in league history to lead team to win against defending Super Bowl champions. ... Buffalo rolled up 203 yards rushing on Baltimore D and is second in league with 608 yards (152 yards per game). ... Rookie LB Kiko Alonso had two interceptions last week and is first Bills rookie with INTs in three consecutive games. ... RBs C.J. Spiller (left ankle) and Fred Jackson (sprained left knee) both hurt last week. Spiller's status uncertain, while Jackson intends to play in brace. ... Third-string RB Tashard Choice could get bulk of carries. He came off bench last season vs. Browns and rushed for 91 yards. ... DE Mario Williams' 69 sacks since 2006 are fifth most in league. ... Bills have been playing nail-biters with all four games decided by seven points or less. ... Browns QB Brian Hoyer will make third straight start. He's 2-0 and coach Rob Chudzinski decided to stick with Hoyer despite Brandon Weeden being healthy after spraining right thumb. ... Hoyer is first Browns QB to win first two starts since Mark Rypien in 1994. ... TE Jordan Cameron has 30 catches and five TDs, making him eighth TE in league history with five scores in September. ... Browns' defense allowing league-best 2.9 yards per rushing attempt. ... Browns only team in league not to give up run of 15 yards or longer. ... Browns LB Barkevious Mingo is first rookie with three sacks in first three games since 2004. ... WR Davone Bess has 19 catches, 12 resulting in first downs and 11 on third down. ... Browns RB Willis McGahee was drafted by Bills in 2003. ... Browns will honor legendary RB Jim Brown during halftime ceremony. Hall of Famer remains team's career leader in yards rushing (12,312), TDs (126) and led league in rushing eight times.

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AP NFL website: http://pro32.ap.org/poll