Alex Amidon had 13 catches for 146 yards and a touchdown as Boston College recovered from a slow start to beat Villanova 24-14 on Saturday and win its first game under coach Steve Addazio.
Andre Williams ran for 114 yards on 23 carries for the Eagles (1-0), who won just twice last season and fired coach Frank Spaziani.
John Robertson ran for 94 yards and passed for 158 more for Villanova (0-1). Jamal Abdur-Rahman caught one TD pass and had a 47-yard touchdown run on a fake punt on the game's opening drive.
The Wildcats, a top 10 team in the Football Championship Subdivision, also led 14-7 before Boston College scored the next 17 points. The Eagles took the lead for good on a two-play drive that included a 36-yard pass to Bobby Wolford and a 24-yard run by Williams to make it 21-14.