Jeff Scott scored on a 75-yard touchdown run with 1:07 left, and Mississippi rallied twice Thursday night to beat Vanderbilt 39-35 in a wild season opener for both teams.
Vanderbilt went up 35-32 on a 34-yard TD pass from Austyn Carta-Samuels to Stephen Scheu with 1:30 left. But Scott beat the Commodores for a TD and the fourth lead change.
Vanderbilt had a final chance to extend the Southeastern Conference's longest winning streak, but Cody Prewitt intercepted a pass off Jordan Matthews' hands with 26 seconds left. That allowed the Rebels to snap a three-game skid to Vanderbilt.
Bo Wallace keyed the Rebels' rally from 11 points down running for two touchdowns and connecting with highly touted freshman Laquon Treadwell for the 2-point conversion.
The Commodores gave up 29 points in the second half, their most since allowing 20 to Florida in their last loss Oct. 13.