Two-time champion Andy Murray was an easy second-round winner Wednesday at the $3 million Western & Southern Open, a hardcourt ATP Masters 1000 event.

After enjoying an opening-round bye, the second-seeded reigning Wimbledon and U.S. Open titlist cruised past 31-year-old Russian veteran Mikhail Youzhny 6-2, 6-3 in 70 minutes at the Lindner Family Tennis Center. Murray piled up five breaks of serve, compared to only one for Youzhny on Day 4.

"I had good anticipation so I was able to chase a lot of balls down and today I managed to get a lot of balls back," Murray said.

"It's not necessarily getting to the ball it's putting it in a position where it's difficult for your opponent to hit a winner off and I think I did that well today."

Murray, who titled here in 2008 and 2011, will meet France's Julien Benneteau in the third round on Thursday.

Seventh-seeded Argentine slugger Juan Martin del Potro dismissed Russian Nikolay Davydenko 7-5, 7-5, while towering American John Isner upended eighth- seeded Frenchman Richard Gasquet 7-6 (8-6), 6-2. The 6-foot-7 former U.S. Open champion del Potro titled in Washington, D.C. two weeks ago by beating the 6- foot-9 Isner in the all-tall final.

Eleventh-seeded Tommy Haas moved on with a 6-4, 6-1 decision against Spaniard Marcel Granollers on Wednesday.

Some other second-round results saw Spanish left-hander Feliciano Lopez get past Frenchman Jeremy Chardy 6-4, 2-2, retired, and Belgian David Goffin hold off last week's Montreal Masters semifinalist Vasek Pospisil, of Canada, 7-5, 1-6, 7-6 (8-6).

This is the last Masters tournament before the U.S. Open, which will commence August 26 in New York.

The 2013 Cincinnati champ will collect $583,800.