Bills rookie EJ Manuel threw for 107 yards and broke a 13-13 tie with a 17-yard TD pass with 14 seconds left in the first half to lead Buffalo past Indianapolis, 44-20 on Sunday.
Manuel was solid, not spectacular in his preseason debut.
He finished 16 of 21 with a quarterback rating of 102.6 and wasn't sacked though he was credited with a fumble after botching a handoff to C.J. Spiller, which led to an Indianapolis field goal.
Manuel played his best on the final drive of the first half when he was 9 of 10 for 68 yards as most of the Bills' starters continued to play against an Indy defense full of backups. The TD pass to Dorin Dickerson gave Buffalo its first lead.
Indy's Andrew Luck played only two series and didn't produce a scoring drive. Backup Matt Hasselbeck played only three series.
Online: AP NFL website www.pro32.ap.org