Two-time reigning champion John Isner and last year's runner-up Lleyton Hewitt were a pair of second-round winners Wednesday at the Hall of Fame Tennis Championships.
The second-seeded 6-foot-10 Isner popped 13 aces in besting France's Adrian Mannarino 6-0, 7-6 (9-7) in 59 minutes, while the fourth-seeded Aussie Hewitt cruised past wild card and 2008 Newport runner-up Prakash Amritraj, of India, 6-2, 6-1 on the grass courts at the International Tennis Hall of Fame and Museum.
Isner's quarterfinal opponent will be fellow 6-foot-10 performer Ivo Karlovic, while the former world No. 1 Hewitt will next be opposed by Czech Jan Hernych.
Meanwhile, third-seeded Dutchman Igor Sijsling handled Japan's Yuichi Sugita 6-3, 6-4 and Poland's Michal Przysiezny ousted eighth-seeded American Rajeev Ram 2-6, 7-5, 6-3. Ram was the surprise Newport champ in 2009.
Przysiezny will next face Frenchman Nicolas Mahut, who made quick work of American Tim Smyczek with a 6-2, 6-4 victory. Mahut was the runner-up here in 2007.
Also on Day 3, the qualifier Hernych held off American Jack Sock 6-3, 4-6, 6-4, journeyman Michael Russell defeated qualifier fellow American Alex Kuznetsov 6-3, 6-4, and the towering Karlovic outlasted Canada's Vasek Pospisil 6-4, 1-6, 6-3. Russell will meet Sijsling in the round of eight.
The winner of this $520,000 event will claim $78,000.