Second-seeded Frenchman Gilles Simon and American Sam Querrey both came up a quarterfinal losers, while French wild card Gael Monfils secured a semifinal berth at the $530,000 Nice Open, a final clay-court French Open tune-up.
Spaniard Pablo Andujar doused Simon 6-4, 7-5, while French wild card Edouard Roger-Vasselin saved nine-of-11 break points in coming from behind to bounce the third-seeded Querrey 3-6, 7-6 (7-2), 6-1 at the Nice Lawn Tennis Club.
Meanwhile, the oft-injured former top-10 star Monfils drilled Dutchman Robin Haase 6-2, 6-3 to set-up a final-four meeting with Andujar.
Also on Day 5, Spaniard Albert Montanes took out France's Paul-Henri Mathieu 6-4, 6-1 in 67 minutes to set-up a semifinal clash with Roger- Vasselin.
Friday's semifinals will not feature any seeded players.
The 2013 Nice champion will earn $95,000.