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Troy Tulowitzki hit a go-ahead, bases-clearing double in the fifth inning that lifted the Colorado Rockies to a 6-3 win over the Arizona Diamondbacks in the second portion of a four-game set.

Wilin Rosario smacked a solo homer among his two hits for the Rockies, who had dropped four of their last five contests coming in on the heels of an eight- game winning streak.

Juan Nicasio (3-0) surrendered three runs -- one earned -- on four hits and a walk over five frames to pick up the win, while Rafael Betancourt fired a 1-2-3 ninth to notch his eighth save of the season.

Brandon McCarthy (0-3) struck out seven over six innings, but allowed six runs on nine hits for Arizona, which had its three-game winning streak snapped.

The D-backs had a 3-2 advantage after four innings before Tulowitzki's two- bagger in the fifth gave Colorado the lead. The bags were full with one away following Jordan Pacheco's single. Carlos Gonzalez then fanned, but Tulowitzki ripped a double into the gap in left-center to clear the bases and make it 5-3.

"Big-time hit by a big-time player," Rockies manager Walt Weiss said of Tulowitzki's double.

Colorado tacked on a run in the sixth when Rosario began the frame by belting a 2-2 pitch into the seats in left-center and push the edge to 6-3.

Arizona wasted a bases-loaded chance in the seventh, as Matt Belisle retired Martin Prado on a pop-up and then fanned Paul Goldschmidt. It was during the inning when Arizona shortstop Didi Gregorius was hit in the helmet by a Josh Outman pitch and forced to leave the game.

"It shows no neurological problems," Arizona manager Kirk Gibson said of Gregorius' injury. "They are doing a CT scan for precautionary measures. We will see what that shows and there is a possibility of a seven-day DL."

Rex Brothers escaped trouble for Colorado in the eighth. With runners on first and second, Brothers struck out Alfredo Marte to cap the frame. It was Brothers' third punchout of the frame.

Earlier, the Rockies plated a pair in the opening frame before Arizona countered by pushing across two in the second and another in the third.

Michael Cuddyer stroked a two-out, two-run single the other way to right- center in the first.

Eric Chavez belted a one-out solo shot and Marte lined an RBI single to center in the second, while Gerardo Parra doubled to begin the third and later scored on Tulowitzki's throwing error on Goldschmidt's grounder to short and make it 3-2 in favor of Arizona.

Game Notes

The Rockies were 3-for-10 with runners in scoring position, while the Diamondbacks went 1-for-9 with RISP ... Tulowitzki tallied his 21st RBI this season.